All those links for the navigation area, do not slice those as image links, i'll kill you. Instead, use text links, they will load alot faster and look just as good, especially if you use a decent font.
Other than that, i think its a decent layout. You could do alot of that layout with css, if you wanted to, and make it look just as good. That would also cut loading times.
My other concern is what your going to do with the left column, looks empty. I hope you have a plan
